| Autor: |
Motti CA; Australian Institute of Marine Science, Australia. C.Motti@aims.gov.au, Freckelton ML, Tapiolas DM, Willis RH |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of natural products [J Nat Prod] 2009 Feb 27; Vol. 72 (2), pp. 290-4. |
| DOI: |
10.1021/np800562m |
| Abstrakt: |
Dereplication of a methanolic extract of the marine sponge Ianthella flabelliformis using FTICR-MS accurate mass determination and MS(n) techniques enabled rapid and unambiguous detection of a new compound among a plethora of known compounds. Isolation of this compound and the known 19-deoxy analogue using the hyphenated technique LC-UV/MS-SPE-NMR was undertaken, and the structures were confirmed, from a single chromatographic run, as 19-hydroxyaraplysillin-I N(20)-sulfamate (1) and araplysillin-I N(20)-sulfamate (2). |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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