Autor: |
de Vries HJ; Sexually Transmitted Infection Outpatient Clinic, Health Service Amsterdam, Amsterdam, The Netherlands. h.j.devries@amc.nl, Smelov V, Middelburg JG, Pleijster J, Speksnijder AG, Morré SA |
Jazyk: |
angličtina |
Zdroj: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2009 Mar 01; Vol. 48 (5), pp. e53-6. |
DOI: |
10.1086/597011 |
Abstrakt: |
Microbial cure of chlamydia proctitis (lymphogranuloma venereum [LGV] and non-LGV) with doxycycline treatment was evaluated by chlamydia DNA and RNA persistence in anal swab specimens. In LGV proctitis, RNA persisted for up to 16 days. In non-LGV chlamydia proctitis, DNA was undetectable after 7 days. These findings support the Centers for Disease Control and Prevention's treatment recommendation of a 21-day doxycycline regimen for LGV proctitis and a 7-day regimen for non-LGV chlamydia proctitis. Delayed microbial cure of LGV proctitis should be considered in improved treatment regimens. |
Databáze: |
MEDLINE |
Externí odkaz: |
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