A comparison of chronaxies for ventricular fibrillation induction, defibrillation, and cardiac stimulation: unexpected findings and their implications.
Autor: | Lawo T; Medical Clinic II (Cardiology), BG University Hospital Bergmannsheil, Bochum, Germany. thomas.lawo@rub.de, Deneke T, Schrader J, Danilovic D, Wenzel B, Buddensiek M, Muegge A |
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Jazyk: | angličtina |
Zdroj: | Journal of cardiovascular electrophysiology [J Cardiovasc Electrophysiol] 2009 Mar; Vol. 20 (3), pp. 307-14. Date of Electronic Publication: 2008 Oct 30. |
DOI: | 10.1111/j.1540-8167.2008.01319.x |
Abstrakt: | Introduction: A low-energy ( Conclusion: It may be reasonable to study whether LEC pulses from 0.25 ms to 0.30 ms in duration and up to 250 V in amplitude would increase therapeutic yield in VT termination without VF induction in humans. Contrary to the current belief, the discrepancy between defibrillation and stimulation chronaxie is not caused by different electrode size. We postulate that the time constant of the fast sodium channel reactivation may be the underlying reason. |
Databáze: | MEDLINE |
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