Gonadotoxic effect of polychlorobiphenyls.

Autor: Gromenko DS; Bashkir State Medical University, Ufa, Bashkiria, Russia., Galimov ShN, Amirova ZK, Abdullina AZ, Gromenko YY, Galimova EF
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2008 Jul; Vol. 146 (1), pp. 70-2.
DOI: 10.1007/s10517-008-0206-3
Abstrakt: The distribution of polychlorobiphenyls (environmental pollutants) in the reproductive organs and fatty tissues of rats was analyzed and selective accumulation of the toxicants in the epididymis, but not in the ovaries, was demonstrated. Reduction of the fertilizing activity of the ejaculate after chronic exposure to polychlorobiphenyls was detected. Mechanisms of spermatogenic dysfunction under conditions of high technogenic load are discussed.
Databáze: MEDLINE