Modified Welsh regimen: a promising therapy for actinomycetoma.

Autor:	Damle DK; Department of Dermatology, B.J. Medical College, Pune, Maharashtra State, India. drdkdamle@rediffmail.com, Mahajan PM, Pradhan SN, Belgaumkar VA, Gosavi AP, Tolat SN, Gokhale NR, Mhaske CB
Jazyk:	angličtina
Zdroj:	Journal of drugs in dermatology : JDD [J Drugs Dermatol] 2008 Sep; Vol. 7 (9), pp. 853-6.
Abstrakt:	Background: Mycetoma has a worldwide geographical distribution which is extremely uneven; however, it is a common disease in India and responsible for causing significant morbidity. Treatment of this condition is often a challenge for the treating dermatologist. The authors report a promising therapy for patients of actinomycotic mycetoma. Methods: This assessment series included 18 patients with a confirmed diagnosis of actinomycetoma, and who had shown a poor response to previous treatments. Patient received a combination therapy of the Welsh regimen (amikacin along with cotrimoxazole) to which rifampicin was added as a third drug. Clinical evaluation included radiology and laboratory investigations. Results: Sixteen patients out of 18 completed the combination therapy, which lead to remission. Two patients were lost to follow-up. Of the 16 patients in remission, no recurrence was observed during a follow-up period of up to 18 months.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu