| Autor: |
Basovskiy YI; Research Institute of Physicochemical Medicine, Federal Agency for Health Care and Social Development, Russia. yur84@mail.ru, Shkarupeta MM, Levitskiy SA, Kostryukova ES, Lazarev VN, Govorun VM |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2008 Apr; Vol. 145 (4), pp. 425-9. |
| DOI: |
10.1007/s10517-008-0108-4 |
| Abstrakt: |
Plasmid vectors encoding hydrophilic (IncB, IncC, IncE, IncG) and hydrophobic (IncC, IncG) domains of C. trachomatis incorporation membrane proteins and reporter green fluorescing proteins were constructed. After transfection of HeLa cells with these plasmid constructs, localization of the complex proteins was determined by laser confocal microscopy. Tropism of hydrophobic domains to compartments constituting the exocytotic pathway in the cell was demonstrated. Location of signal/sorting sequences responsible for specific localization was determined. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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