Post-thrombotic syndrome after total hip arthroplasty is uncommon.

Autor: Mant MJ; Department of Medicine, Division of Hematology and Oncology, University of Alberta, Edmonton, Canada., Eurich DT, Russell DB, Majumdar SR
Jazyk: angličtina
Zdroj: Acta orthopaedica [Acta Orthop] 2008 Dec; Vol. 79 (6), pp. 794-9.
DOI: 10.1080/17453670810016876
Abstrakt: Background: Deep vein thrombosis (DVT), usually asymptomatic, is common after total hip arthroplasty (THA). Post-thrombotic syndrome (PTS) is a potential late complication of DVT, but there is limited data on its occurrence.
Patients and Methods: This was a prospective cohort study of subjects at one hospital who had participated in a trial of thromboprophylaxis for THA and who had postoperative venography. Data were collected at baseline and 2-4 years later to ascertain symptoms of PTS using a modification of a validated scoring system. Outcomes were collected without knowledge of baseline characteristics or venogram results. Potential predictors of PTS were explored using exact logistic regression analyses.
Results: The cohort (n=188) had a mean age of 63 years, 51% were male, 35% had a BMI of>30, and 4% had a prior history of DVT. 25 patients (13%) had DVTs on venography. 12 patients (6%, 95% CI: 3-11) subsequently developed symptoms consistent with PTS, 7 with bilateral symptoms. Most affected limbs (15 of 19) had no postoperative DVT. No statistically significant predictors of PTS were found.
Interpretation: Symptoms of PTS are infrequent after THA in patients who receive some form of thromboprophylaxis. Our findings, which are consistent with the existing literature, suggest that there is a potential benefit to giving thromboprophylaxis for reduction of symptomatic PTS.
Databáze: MEDLINE
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