[Evaluation of the carcinogenic activity of phenol-free coal-tar creolin].

Autor: Pylev LN, Vasil'eva LA, Levinskiĭ SS, Khitrovo IA, Khrustalev SA, Trukhina GM
Jazyk: ruština
Zdroj: Gigiena i sanitariia [Gig Sanit] 2008 Sep-Oct (5), pp. 81-4.
Abstrakt: When orally administered to rats and mice, phenol-free coal-tar creolin containing 0.018+/-0.002 g/kg of benz(a)pyrene showed no carcinogenic activity. The discrepancy of the biological activity and content of carcinogen in the combined mixture, the role of their components in carcinogenesis, the value of control experiments, and historic control test, and the implication of these rapid tests in the evaluation of their carcinogenicity is shown.
Databáze: MEDLINE