Short communication: Molecular characterization of HIV type 1 BF pol recombinants from São Paulo, Brazil.

Autor: de Souza AC; Instituto de Medicina Tropical, Universidade de São Paulo, Laboratório de Virologia, LIM52, São Paulo, SP, Brazil., de Oliveira CM, Rodrigues CL, Silva SA, Levi JE
Jazyk: angličtina
Zdroj: AIDS research and human retroviruses [AIDS Res Hum Retroviruses] 2008 Dec; Vol. 24 (12), pp. 1521-5.
DOI: 10.1089/aid.2008.0089
Abstrakt: In the Brazilian HIV-1 epidemic, subtypes B, C, and F1 are cocirculating in the population. Sequences of the partial pol gene from 463 HIV-1-infected patients were obtained from plasma samples and viral subtype was characterized. BF recombinants were found in 8% of the samples. Fifteen different patterns were observed. A CRF28_BF and CRF29_BF structure was found in 29.7% of the samples, CRF12_BF in 13.5%, and CRF39_BF in 2.7%. Two other patterns were identified in each of three samples. These findings could indicate a new CRF description, but to determine this a full length study is required.
Databáze: MEDLINE