Rhodium catalysed conjugate addition of a chiral alkenyltrifluoroborate salt: the enantioselective synthesis of hermitamides A and B.

Autor: Frost CG; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK. c.g.frost@bath.ac.uk, Penrose SD, Gleave R
Jazyk: angličtina
Zdroj: Organic & biomolecular chemistry [Org Biomol Chem] 2008 Dec 07; Vol. 6 (23), pp. 4340-7. Date of Electronic Publication: 2008 Oct 18.
DOI: 10.1039/b812897a
Abstrakt: The concise enantioselective synthesis of hermitamides A and B is presented utilising a rhodium catalysed conjugate addition reaction to introduce the side chain and chiral information in a single step via an alkenyltrifluoroborate salt.
Databáze: MEDLINE