Does uric acid provide information about maternal condition and fetal outcome in pregnant women with hypertension?

Autor: Paula LG; Programa de Pós-graduação em Clínica Médica e Ciências da Saúde (Nefrologia), Faculdade de Medicina/Hospital São Lucas, Pontificia Universidade Católica do Rio Grande do Sul., Porto Alegre, RS, Brazil. leticiagpaula@terra.com.br, da Costa BE, Poli-de-Figueiredo CE, Antonello IC
Jazyk: angličtina
Zdroj: Hypertension in pregnancy [Hypertens Pregnancy] 2008; Vol. 27 (4), pp. 413-20.
DOI: 10.1080/10641950801955709
Abstrakt: Objective: To evaluate associations between maternal serum uric acid (UA) levels, maternal status, and fetal outcome.
Methods: Maternal UA, urinary protein-creatinine ratio (P/C), blood pressure (BP), gestational age at delivery, and birth weight were evaluated in hypertensive pregnant women (n = 58). These were divided into two groups: high UA (> or =357 micromol/L) or normal UA (<357 micromol/L).
Results: Maternal diastolic BP and P/C ratio were higher in pregnant women with elevated UA levels. Systolic BP, gestational age and birth weight were not significantly different.
Conclusion: UA equal or above 357 micromol/L in pregnant hypertensive women was associated with proteinuria and diastolic BP, but not with fetal outcome.
Databáze: MEDLINE
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