| Autor: |
Miners JO; Department of Clinical Pharmacology, Flinders Medical Centre, Bedford Park, Adelaide, Australia., Lillywhite KJ |
| Jazyk: |
angličtina |
| Zdroj: |
Biochemical pharmacology [Biochem Pharmacol] 1991 Mar 01; Vol. 41 (5), pp. 838-41. |
| DOI: |
10.1016/0006-2952(91)90090-r |
| Abstrakt: |
The data suggest that the 4MU-UDPGT activity of human liver microsomes probably contributes to the glucuronidation of a limited number of clinically used drugs. However, confirmation of this ultimately requires studies to be performed with purified isozymes, cDNAs expressed in cell culture, or specific inhibitory antibodies. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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