Evaluation of a dynamic bayesian belief network to predict osteoarthritic knee pain using data from the osteoarthritis initiative.

Autor: Watt EW; University of California Los Angeles, Los Angeles, CA, USA., Bui AA
Jazyk: angličtina
Zdroj: AMIA ... Annual Symposium proceedings. AMIA Symposium [AMIA Annu Symp Proc] 2008 Nov 06, pp. 788-92. Date of Electronic Publication: 2008 Nov 06.
Abstrakt: The most common cause of disability in older adults in the United States is osteoarthritis. To address the problem of early disease prediction, we have constructed a Bayesian belief network (BBN) composed of knee OA-related symptoms to support prognostic queries. The purpose of this study is to evaluate a static and dynamic BBN--based on the NIH Osteoarthritis Initiative (OAI) data--in predicting the likelihood of a patient being diagnosed with knee OA. Initial validation results are promising: our model outperforms a logistic regression model in several designed studies. We can conclude that our model can effectively predict the symptoms that are commonly associated with the presence of knee OA.
Databáze: MEDLINE