An unusual variant of Cushing syndrome.
| Autor: | Ganesh HK; Department of Endocrinology, Seth GS Medical College and KEM Hospital, Mumbai, Maharashtra, India., George J, Vimal MV, Bandgar T, Menon PS, Shah NS |
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| Jazyk: | angličtina |
| Zdroj: | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists [Endocr Pract] 2008 Sep; Vol. 14 (6), pp. 717-20. |
| DOI: | 10.4158/EP.14.6.717 |
| Abstrakt: | Objective: To discuss the initial clinical manifestations of primary pigmented nodular adrenocortical disease. Methods: We present a case report of a 4-year-old boy who had the classic clinical features of Cushing syndrome. Results of hormonal investigations are reviewed, and histopathologic findings are illustrated. Results: Investigations revealed adrenocorticotropic hormone (corticotropin)-independent Cushing syndrome. Findings on magnetic resonance imaging of the pituitary gland and abdomen were within normal limits. The patient underwent bilateral adrenalectomy. The histopathologic features were consistent with primary pigmented nodular adrenocortical disease. Conclusion: Primary pigmented nodular adrenocortical disease should be suspected in patients with corticotropin-independent Cushing syndrome who have normal findings on adrenal imaging. |
| Databáze: | MEDLINE |
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