| Autor: |
Ott P; Medicinsk Hepato-gastroenterologisk Afdeling V, Arhus Universitetshospital, Arhus Sygehus, DK-8000 Arhus C. peott@as.aaa.dk, Grønbaek H, Clemmesen JO, Clausen MR, Wettergren A, Havelund T, Feldager E, Bendtsen F, Hansen BA, Tage-Jensen U, Larsen LP, Vilstrup H |
| Jazyk: |
dánština |
| Zdroj: |
Ugeskrift for laeger [Ugeskr Laeger] 2008 Nov 03; Vol. 170 (45), pp. 3671-3. |
| Abstrakt: |
The risk of severe bleeding after liver biopsy is estimated to be 1:12,000 in patients with near normal coagulation (INR < 1,5 and platelet count > 60 billion /l). Beyond these limits, the risk is higher, but still uncertain. The Danish guidelines require INR > 1.5, platelet count < 40 billion /l and normal APTT. In some instances the risk of not knowing the histology is so high that a biopsy is considered even with a more disturbed coagulation. Vitamin K, freshly frozen plasma and recombinant activated factor VII may reduce the risk of bleeding in specific situations, but no firm recommendations can be given. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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