Prostatic squamous metaplasia in a cat with interstitial cell neoplasia in a retained testis.

Autor: Tucker AR; Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA., Smith JR
Jazyk: angličtina
Zdroj: Veterinary pathology [Vet Pathol] 2008 Nov; Vol. 45 (6), pp. 905-9.
DOI: 10.1354/vp.45-6-905
Abstrakt: An 11-year-old cat with a retained testis was presented with a chronic history of dysuria and bladder atony. Medical therapy failed to alleviate the clinical signs. Contrast radiography demonstrated a diffusely narrowed urethra. During a celiotomy and prepubic urethrostomy, a retained testis, stenosed urethra, and irregularly enlarged prostate were observed. Histopathologic diagnosis was retained testis with a well-differentiated interstitial cell tumor, a poorly differentiated interstitial cell tumor, and marked squamous metaplasia of the prostatic epithelium with suppurative prostatitis. Neoplastic interstitial cells were immunoreactive for Melan A, consistent with reports of Melan A expression in steroid hormone-producing tissue. This is the first report of prostatic squamous metaplasia associated with testicular neoplasia in a felid.
Databáze: MEDLINE