| Autor: |
Ratsimbasoa A; Malaria Research Unit, Institut Pasteur de Madagascar, Antananarivo, Madagascar., Fanazava L, Radrianjafy R, Ramilijaona J, Rafanomezantsoa H, Ménard D |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2008 Nov; Vol. 79 (5), pp. 670-2. |
| Abstrakt: |
We assessed the performance of two new commercially available rapid diagnostic tests (RDTs) for malaria (SD Bioline Malaria Ag Pf test and Ag Pf/Pan test) in 200 patients with uncomplicated malaria between August and October 2007 in Madagascar. Results of the two RDTs were compared with those obtained by microscopy and real-time polymerase chain reaction. The sensitivity and specificity for detection of Plasmodium falciparum were 93% and 98.9%, respectively, for the SD Bioline Malaria Ag Pf test and 92.9% and 98.9% for the SD Bioline Malaria Ag Pf/Pan test. The sensitivity of the SD Bioline Malaria Ag Pf/Pan test was much lower for detection of other species (63.6%). The sensitivity of the two new assays decreased to 77.3% at parasitemia levels < 100 parasites/microL for detection of P. falciparum. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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