Spirochetes in atrophic skin lesions accompanied by minimal host response in a child with Lyme disease.

Autor: Gellis SE; Department of Dermatology, Pathology, Tufts University School of Medicine, Boston, MA., Stadecker MJ, Steere AC
Jazyk: angličtina
Zdroj: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 1991 Aug; Vol. 25 (2 Pt 2), pp. 395-7.
DOI: 10.1016/0190-9622(91)70213-l
Abstrakt: Acrodermatitis chronica atrophicans, which has rarely been observed in the United States, is a late skin manifestation of Lyme borreliosis. A 12-year-old girl who spent summers on Cape Cod presented with a 2-year history of hyperpigmentation and atrophy of the skin on the hands, wrists, and ankles. The skin biopsy specimen of an affected area showed mild dermal fibrosis, a few inflammatory cells, and spirochetes morphologically compatible with Borrelia burgdorferi. An IgG antibody response to B. burgdorferi could be elicited by immunoblotting, but not by enzyme-linked immunosorbent assay. We conclude that this patient had chronic Lyme borreliosis manifested only by indolent infection of the skin.
Databáze: MEDLINE