Transfer of peanut allergy from the donor to a lung transplant recipient.

Autor: Khalid I; Department of Pulmonary and Critical Care Medicine, Henry Ford Health System, Detroit, Michigan 48202, USA. doc_ik@yahoo.com, Zoratti E, Stagner L, Betensley AD, Nemeh H, Allenspach L
Jazyk: angličtina
Zdroj: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2008 Oct; Vol. 27 (10), pp. 1162-4. Date of Electronic Publication: 2008 Aug 27.
DOI: 10.1016/j.healun.2008.07.015
Abstrakt: Among solid organs, transfer of peanut allergy from donor to recipient has been implicated after liver transplantation. We report the first case in which such transfer occurred after a lung transplant. A 42-year-old woman with history of sarcoidosis underwent a successful bilateral lung transplant from a donor who died from anaphylactic shock after eating peanut-related food. Seven months later, she ate a peanut butter cookie at a transplant support group meeting. Immediately thereafter, she developed an anaphylactic reaction, but survived with prompt treatment. During subsequent follow-up, she could recall three prior episodes of wheezing and difficulty breathing after eating peanut-related foods. The first episode occurred 4 days after the transplant. Prior to her transplant, she never had problems eating peanuts. Skin-prick testing confirmed peanut sensitization. She avoided peanuts and, although her skin-prick test became negative, she still manifested peanut allergy when formally challenged orally with the food. She was advised to continue abstaining from all peanut-related foods. This case emphasizes the importance of considering donor allergy transfer when caring for all solid-organ transplant recipients in order to avoid a life-threatening event.
Databáze: MEDLINE