Autor: |
Eliseeva IYa, Ravkina LI, Karmysheva VYa |
Jazyk: |
angličtina |
Zdroj: |
Acta virologica [Acta Virol] 1977 May; Vol. 21 (3), pp. 222-7. |
Abstrakt: |
A strain designated 42-Edmonston was isolated from the brain of a Syrian hamster 30 days after inoculation during the neonatal period with the reference "wild" measles virus strain Edmonston which produced a latent infection accompanied by production of measles antibody and insignificant pathomorphological changes. Intracerebral inoculation with the 42-Edmonston strain of newborn, one day-and 5-7-day-old Syrian hamsters resulted in the development of acute measles encephalitis with typical clinical symptoms and pathomorphological changes. It is suggested that selection and adaptation of a neurotropic measles virus variant probably had occurred in the course of virus persistence in the Syrian hamster brain. |
Databáze: |
MEDLINE |
Externí odkaz: |
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