Autor: |
Jepras RI; Division of Biotechnology, P.H.L.S. Centre for Applied Microbiology and Research, Porton Down, Wilts, U.K., Rarity J, Perkins EA, Clarke DJ, Carr RJ, Atkinson T |
Jazyk: |
angličtina |
Zdroj: |
Biochemical Society transactions [Biochem Soc Trans] 1991 Apr; Vol. 19 (2), pp. 513-4. |
DOI: |
10.1042/bst0190513 |
Abstrakt: |
Following a recent successful application of p.c.s. to liquid chromatography in the biotechnology industry, its usefulness as a contamination monitor in the fermentation industry was assessed. It was found that: (i) the intensity bias of the technique limits its uses to the detection of contaminants when they are larger than the host; (ii) the inherent heterogeneity of microbial cultures prevents the use of multiangle studies, and (iii) the large size of bacteria make the use of p.c.s. in flowing, on-line systems impractical. |
Databáze: |
MEDLINE |
Externí odkaz: |
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