| Autor: |
Quasdorf KW; Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095, USA., Tian X, Garg NK |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of the American Chemical Society [J Am Chem Soc] 2008 Nov 05; Vol. 130 (44), pp. 14422-3. Date of Electronic Publication: 2008 Oct 08. |
| DOI: |
10.1021/ja806244b |
| Abstrakt: |
The first cross-coupling of acylated phenol derivatives has been achieved. In the presence of an air-stable Ni(II) complex, readily accessible aryl pivalates participate in the Suzuki-Miyaura coupling with arylboronic acids. The process is tolerant of considerable variation in each of the cross-coupling components. In addition, a one-pot acylation/cross-coupling sequence has been developed. The potential to utilize an aryl pivalate as a directing group has also been demonstrated, along with the ability to sequentially cross-couple an aryl bromide followed by an aryl pivalate, using palladium and nickel catalysis, respectively. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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