The use and midium-term evaluation of decellularized allograft cusp in the surgical treatment of the tetralogy of fallot.

Autor:	Mulinari LA; Departamento de Cirurgia, Universidade Federal do Paraná. dr.mulinari@terra.com.br, Navarro FB, Pimentel GK, Miyazaki SM, Binotto CN, Pelissari EC, Miyague NI, da Costa FD
Jazyk:	English; Portuguese
Zdroj:	Revista brasileira de cirurgia cardiovascular : orgao oficial da Sociedade Brasileira de Cirurgia Cardiovascular [Rev Bras Cir Cardiovasc] 2008 Apr-Jun; Vol. 23 (2), pp. 197-203.
DOI:	10.1590/s0102-76382008000200008
Abstrakt:	Objective: To describe the technique of implantation and to show the echocardiographic follow-up of the decellularized cusps allografts used in patients with tetralogy of fallot. Methods: Fifteen patients underwent this implantation between March 2005 and August 2007 and they were clinically followed-up. An echocardiogram was performed to evaluate the morphofunctional result of the allografts. Results: The mean follow-up was 12.7 months (1-25 months). The echocardiography results showed that pulmonary insufficiency was mild in nine (60%) patients, moderate in three (20%) patients, and severe in three (20%) patients. The results also showed that the systolic right ventricle function was normal in 13 (86.7%) and that there was mild dysfunction in two (13.3%). Eleven (73.4%) patients did not present any gradient in the right ventricular outflow tract and four (26.6%) presented mild stenosis. The mobility of the cusps were normal in all cases and there was no thickness larger than 1.5 mm. There was no calcification; 14 patients (93.3%) presented Z score between -1 and 0,7 and one patient presented dilated pulmonary annulus with a Z score of + 2.5. Conclusion: In midium-term follow-up, the decellularized allograft seemed to be a good option for right ventricle outflow tract enlargement in patients underwent tetralogy of Fallot.
Databáze:	MEDLINE
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