Autor: |
Paula LP; Serviço de Endicrinologia, Hospital de Clínicas de Porto Alegre, Programa de Pós-Graduação em Ciências Médicas: Endocrinologia, Metabolismo e Nutrição, Faculdade de Medicina, UFRGS, Porto Alegre, RS, Brazil. endo.endoped@yahoo.com.br, Czepielewski MA |
Jazyk: |
portugalština |
Zdroj: |
Arquivos brasileiros de endocrinologia e metabologia [Arq Bras Endocrinol Metabol] 2008 Jul; Vol. 52 (5), pp. 734-44. |
DOI: |
10.1590/s0004-27302008000500004 |
Abstrakt: |
The diagnostic approach to growth hormone deficiency (GHD) in children with short stature (SS) is controversial. Here we review the available methodology and present prospective data obtained in a cohort of patients with SS suggesting the use of screening test followed by the confirmation test. Thus, the children with SS should be submitted to clinical and laboratorial evaluation to exclude of chronic and genetic diseases. In addition patients with height<3 percentile or growth velocity-1 SD, the growth velocity should have observed and GH/IGF-1 axis re-evaluated if the growth pattern is not satisfactory. |
Databáze: |
MEDLINE |
Externí odkaz: |
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