Concise synthesis of bicyclic aminals and their evaluation as precursors to the sarain core.

Autor: Price Mortimer AJ; Department of Chemistry, University College London, Christopher Ingold Building, 20 Gordon Street, London, UKWC1H 0AJ., Pang PS, Aliev AE, Tocher DA, Porter MJ
Jazyk: angličtina
Zdroj: Organic & biomolecular chemistry [Org Biomol Chem] 2008 Aug 21; Vol. 6 (16), pp. 2941-51. Date of Electronic Publication: 2008 Jun 19.
DOI: 10.1039/b806031b
Abstrakt: A number of bicyclic aminals have been prepared in a stereospecific manner as potential precursors to the core structure of the sarain alkaloids. Rearrangement of these aminals to new diazabicyclic and diazatricyclic systems has been observed under various conditions.
Databáze: MEDLINE