Effect of selank on cognitive processes after damage inflicted to the cerebral catecholamine system during early ontogeny.

Autor: Semenova TP; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino., Kozlovskaya MM, Zakharova NM, Kozlovskii II, Zuikov AV
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2007 Nov; Vol. 144 (5), pp. 689-91.
DOI: 10.1007/s10517-007-0406-2
Abstrakt: Effects of selank on learning, memory, and attention to sensory stimuli of different modality were studied in adult Wistar rats treated with 6-hydroxydopamine (neurotoxin selectively damaging catecholaminergic neurons and their terminals) during the first 3 days of life. Selank (300 microg/kg) restored cognitive processes disordered by chronic artificial inhibition of the cerebral catecholaminergic system.
Databáze: MEDLINE