| Autor: |
Ewan KB; School of Biosciences, Biomedical Sciences Building, Museum Avenue, Cardiff, CF10 3US, UK., Dale TC |
| Jazyk: |
angličtina |
| Zdroj: |
Current drug targets [Curr Drug Targets] 2008 Jul; Vol. 9 (7), pp. 532-47. |
| DOI: |
10.2174/138945008784911787 |
| Abstrakt: |
There has been a surge of interest in the therapeutic targeting of the Wnt pathway following the demonstration that it is activated in a wide variety of tumors and that blocking aberrant signaling promoted tumor cell apoptosis or differentiation. This review describes recent therapeutic approaches and discusses potential opportunities for intervention at multiple levels within the Wnt pathway. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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