EUS-guided fine needle aspiration with and without trucut biopsy of pancreatic masses.

Autor:	Shah SM; Pancreatobiliary Interest Group at Sylvester Cancer Center, Miller School of Medicine, University of Miami, Miami, FL 33101, USA., Ribeiro A, Levi J, Jorda M, Rocha-Lima C, Sleeman D, Hamilton-Nelson K, Ganjei-Azar P, Barkin J
Jazyk:	angličtina
Zdroj:	JOP : Journal of the pancreas [JOP] 2008 Jul 10; Vol. 9 (4), pp. 422-30. Date of Electronic Publication: 2008 Jul 10.
Abstrakt:	Context: Endoscopic ultrasound-guided trucut biopsy (EUS TCB) has a lower yield than fine needle aspiration (FNA) in pancreatic masses but the additional use of TCB to FNA may improve the diagnostic accuracy over FNA alone. Objective: To compare the yield of EUS FNA alone or combined with EUS TCB for diagnosis of pancreatic masses. Design: Single center retrospective case control study conducted at academic tertiary center. Study conducted between March 2004 and April 2007. Participants: A total of 126 consecutive patients referred for EUS guided biopsy of pancreatic mass; three patients excluded from analysis, final cohort comprised 123 patients (108 malignant and 15 benign). EUS FNA was performed in 72 patients and EUS FNA+TCB was performed in 51 patients. Main Outcome Measures: The diagnostic performance of EUS FNA versus EUS FNA+TCB was compared. Results: The sensitivity, specificity and frequency of cases correctly identified for malignancy of FNA alone were 87.1% (54/62), 100% (10/10) and 88.8% (64/72), while for the combination of FNA+TCB they were: 95.7% (44/46), 100% (5/5) and 96.0% (49/51), respectively (P=0.184, 1.000, and 0.193 FNA versus FNA+TCB). No major complication occurred in either group. Conclusion: FNA+TCB can be safely performed in selected lesions but sensitivity is not statistically improved over FNA alone (95.7% versus 87.1%).
Databáze:	MEDLINE
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