[Statins and neuromuscular pathology].
| Autor: | Turpin-Fenoll L; Sección de Neurología, Hospital Virgen de la Luz, Cuenca, España. lturdoc@hotmail.com, Millan-Pascual J, Martin-Estefania C |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Revista de neurologia [Rev Neurol] 2008 Jul 1-15; Vol. 47 (1), pp. 46-51. |
| Abstrakt: | Introduction: Statins represent a group of pharmaceutical agents with proven effectiveness and scarce side effects; however, their widespread use increases the probability of the appearance of such adverse effects. Development: We reviewed the articles that have been published on myotoxicity, neurotoxicity and other cases of disorders affecting the peripheral nervous system, both in reviews and in clinical trials and isolated cases. The frequency of appearance, clinical repercussion, proposed physiopathogenetic mechanisms were analysed in order to draw conclusions regarding the therapeutic attitude that should be adopted. Conclusions: Generally speaking they are safe pharmaceuticals, but the physician must pay attention to the appearance of possible side effects, given their potential reversibility and lower degree of severity if they are diagnosed at an early stage. |
| Databáze: | MEDLINE |
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