| Autor: |
Roche PW; Mycobacterial Research Laboratories, Anandaban Leprosy Hospital, Kathmandu, Nepal., Britton WJ, Neupane KD, Failbus SS, Cho SN, Theuvenet WJ |
| Jazyk: |
angličtina |
| Zdroj: |
The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 1991 Jun; Vol. 44 (6), pp. 702-8. |
| DOI: |
10.4269/ajtmh.1991.44.702 |
| Abstrakt: |
We have examined the Mycobacterium leprae phenolic glycolipid-I (PG-I) antigen levels in the sera of 45 multibacillary leprosy patients commencing chemotherapy. The PG-I antigen levels correlated with the bacterial and morphological indices, but not with the serum IgM anti-PG-I antibody levels. Antigen levels were significantly higher in patients with diffuse skin infiltration, but did not vary significantly with other parameters reflecting the duration and extent of untreated disease. The PG-I antigen levels in 27 patients examined serially decreased consistently over the first year of multidrug therapy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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