Autor: |
Panchenko LF, Olfer'ev AM, Loktaeva TD, Ivkov NN, Komissarova TIu |
Jazyk: |
ruština |
Zdroj: |
Ukrains'kyi biokhimichnyi zhurnal [Ukr Biokhim Zh] 1976 Jul-Aug; Vol. 48 (4), pp. 455-9. |
Abstrakt: |
The sulphydryl groups of nonprotein thiols and proteins of mitochondria, activity of enzymes, oxidative phosphorylation and swelling of these organellas were studied as affected by the thiol-oxidizing agents. Diamide and azoester are shown to oxidize SH-groups of mitochondria, inhibit isocytrate dehydrogenase and succinate: cytochrome oxidation and inhibits energy-dependent swelling of mitochondria. Under the effect of azoester the rate of oxygen consumption by mitochondria increases and there occurs their sharp swelling. |
Databáze: |
MEDLINE |
Externí odkaz: |
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