[Endoscopic treatment of vesicoureteral reflux: histologic findings].

Autor: López Díaz M; Servicio de Cirugía Pediátrica, Hospital Universitario 12 de Octubre, Madrid, España. maria_lopez_d@yahoo.es, López Vázquez F, Gómez Fraile A, Aransay Bramtot A, Cabezalí Barbancho D, Tejedor Sánchez R
Jazyk: Spanish; Castilian
Zdroj: Archivos espanoles de urologia [Arch Esp Urol] 2008 Mar; Vol. 61 (2), pp. 112-6.
DOI: 10.4321/s0004-06142008000200003
Abstrakt: Objectives: Vesicoureteral reflux is a pathologic entity with different forms of therapeutic management, one of which is endoscopic injection of various materials. We show some histological changes produced by these materials in the bladder wall.
Methods: We study three samples of intravesical ureter from three children suffering vesicoureteral reflux. The ureters were obtained during ureteral reimplantation surgery.
Results: We show the changes found with various materials under study (polytetrafluorethylene, polydimethylsiloxane, hyaluronic acid and dextranomer copolimer) observing less conjunctive tissue with the two latter and with the more encapsulated hyaluronic acid - dextranomer copolimer.
Conclusions: Migrations and granulomas are described with various materials and we ascertained the presence of foreign body reaction and fibrosis within the bladder wall. More studies in human beings are required to determine the best product for endoscopic injection.
Databáze: MEDLINE