Breast magnetic resonance imaging for preoperative locoregional staging.

Autor: Hollingsworth AB; Department of Surgery, Mercy Health Center, Oklahoma City, OK, USA. ahollingsworth@ok.mercy.net, Stough RG, O'Dell CA, Brekke CE
Jazyk: angličtina
Zdroj: American journal of surgery [Am J Surg] 2008 Sep; Vol. 196 (3), pp. 389-97. Date of Electronic Publication: 2008 Apr 23.
DOI: 10.1016/j.amjsurg.2007.10.009
Abstrakt: Background: Breast magnetic resonance imaging (MRI) has been recommended increasingly in the preoperative setting for patients newly diagnosed with malignancy to evaluate tumor extent, multicentricity, and contralateral disease.
Methods: Results of conventional imaging, breast MRI, and pathology were analyzed from 603 consecutive breast cancer patients who underwent MRI preoperatively. The focus of this retrospective study was imaging-histologic correlation.
Results: Reoperation for positive margins after lumpectomy occurred in 8.8% of patients. Multicentricity was identified by MRI alone in 7.7% of patients, whereas 3.7% were found to have contralateral cancer by MRI. The sensitivity of MRI was 93% in detecting multicentric disease and 88% for contralateral disease, whereas sensitivity for conventional imaging was 46% and 19%, respectively. Unsuspected disease was identified by MRI equally for invasive ductal and ductal carcinoma in situ histology, whereas multicentricity was found more frequently with invasive lobular carcinoma.
Conclusions: Breast MRI is recommended for preoperative evaluation of the newly diagnosed breast cancer patient.
Databáze: MEDLINE
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