| Autor: |
Pinheiro AL; Department of Propedeutica and Clínica Integrada, Laser Center, School of Dentistry, Federal University of Bahia, Salvador, BA, Brazil. albp@ufba.br, Martinez Gerbi ME, de Assis Limeira F Jr, Carneiro Ponzi EA, Marques AM, Carvalho CM, de Carneiro Santos R, Oliveira PC, Nóia M, Ramalho LM |
| Jazyk: |
angličtina |
| Zdroj: |
Lasers in medical science [Lasers Med Sci] 2009 Mar; Vol. 24 (2), pp. 234-40. Date of Electronic Publication: 2008 Apr 17. |
| DOI: |
10.1007/s10103-008-0556-0 |
| Abstrakt: |
The aim of the investigation was to assess histologically the effect of laser photobiomodulation (LPBM) on a repair of defects surgically created in the femurs of rats. Forty-five Wistar rats were divided into four groups: group I (control); group II (LPBM); group III (hydroxyapatite guided bone regeneration; HA GBR); group IV (HA GBR LPBM). The animals in the irradiated groups were subjected to the first irradiation immediately after surgery, and it was repeated every day for 2 weeks. The animals were killed 15 days, 21 days and 30 days after surgery. When the groups irradiated with implant and membrane were compared, it was observed that the repair of the defects submitted to LPBM was also processed faster, starting from the 15th day. At the 30th day, the level of repair of the defects was similar in the irradiated groups and those not irradiated. New bone formation was seen inside the cavity, probably by the osteoconduction of the implant, and, in the irradiated groups, this new bone formation was incremental. The present preliminary data seem to suggest that LPMB therapy might have a positive effect upon early wound healing of bone defects treated with a combination of HA and GBR. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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