| Autor: |
Unal M; Department of Biology, Arts and Sciences Faculty, Marmara University, Goztepe 81040, Istanbul, Turkey., Palavan-Unsal N, Tufekci MA |
| Jazyk: |
angličtina |
| Zdroj: |
Acta biologica Hungarica [Acta Biol Hung] 2008 Mar; Vol. 59 (1), pp. 93-102. |
| DOI: |
10.1556/ABiol.59.2008.1.8 |
| Abstrakt: |
The genotoxic and cytotoxic effects of exogenous polyamines (PAs), putrescine (Put), spermidine (Spd), spermine (Spm) and PA biosynthetic inhibitors, alpha-difluoromethylornithine (DFMO), cyclohexilamine (CHA), methylglioxal bis-(guanylhydrazone) (MGBG) were investigated in the root meristems of Allium cepa L. The reduction of mitotic index and the induction of chromosomal aberrations such as bridges, stickiness, c-mitotic anaphases, micronuclei, endoredupliction by PAs and PA biosynthetic inhibitors were observed and these were used as evidence of genotoxicity and cytotoxicity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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