Discrepancy between fluorescein angiography and optical coherence tomography in detection of macular disease.

Autor:	Kozak I; Jacobs Retina Center at Shiley Eye Center, University of California at San Diego, La Jolla, California 92037, USA., Morrison VL, Clark TM, Bartsch DU, Lee BR, Falkenstein I, Tammewar AM, Mojana F, Freeman WR
Jazyk:	angličtina
Zdroj:	Retina (Philadelphia, Pa.) [Retina] 2008 Apr; Vol. 28 (4), pp. 538-44.
DOI:	10.1097/IAE.0b013e318167270b
Abstrakt:	Purpose: To compare high-resolution optical coherence tomography (OCT) and fluorescein angiography (FA) in detection of macular edema (ME) of various etiologies. Methods: In a retrospective study over a 12-month period at one retina center, data for consecutive eyes that had undergone simultaneous conventional FA (HRA; Heidelberg Engineering, Vista, CA) and StratusOCT (Carl Zeiss Meditec, Dublin, CA) to rule out ME were reviewed. A subset of patients underwent additional examination with extremely high-resolution (6-microm)/ultrahigh-speed spectral OCT/scanning laser ophthalmoscopy (OTI, Inc., Toronto, Ontario, Canada). Results: Of 1,272 eyes, 1,208 (94.97%) had the finding of ME or subretinal fluid confirmed by both techniques. There were 49 eyes (3.86%) for which FA showed dye leakage in the macular area and OCT showed normal foveal contour. Of 10 eyes in this group that underwent imaging with ultrahigh-speed spectral OCT/scanning laser ophthalmoscopy, 8 had subtle diffuse lucencies in the retina. For 15 eyes (1.17%), OCT showed intraretinal and subretinal fluid, which was missed by FA. Conclusions: Both FA and high-resolution OCT are highly sensitive techniques and correlate well in detection of ME. However, there is a small chance that when performed alone they might miss existing subtle ME.
Databáze:	MEDLINE
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