Chronic eosinophilic pneumonia secondary to long-term use of nitrofurantoin: high-resolution computed tomography findings.

Autor: Martins RR; Armed Forces Hospital - Brasília, Brazil. sanemar@correioweb.com.br, Marchiori E, Viana SL, Grillo Júnior LS, Capelozzi VL, Valença LM
Jazyk: English; Portuguese
Zdroj: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia [J Bras Pneumol] 2008 Mar; Vol. 34 (3), pp. 181-4.
DOI: 10.1590/s1806-37132008000300009
Abstrakt: The authors report the case of a female patient who developed chronic eosinophilic pneumonia secondary to long-term use of nitrofurantoin for prophylaxis of recurrent urinary tract infections due to urethral stenosis. On high-resolution computed tomography scans, the pulmonary reaction to nitrofurantoin most commonly manifests as an interstitial-alveolar pattern in both lung bases. However, in this case, the alterations were most pronounced in the periphery of the upper lobes. In itself, this tomographic profile is strongly indicative of chronic eosinophilic pneumonia. The patient had previously been submitted to an open lung biopsy. The diagnosis of chronic eosinophilic pneumonia was confirmed through a review of the biopsy.
Databáze: MEDLINE