Systolic dysfunction portends increased mortality among those waiting for renal transplant.

Autor: de Mattos AM; Divisions of Nephrology, University of Alabama at Birmingham, Birmingham, Alabama, USA. angelo.demattos@ucdmc.ucdavis.edu, Siedlecki A, Gaston RS, Perry GJ, Julian BA, Kew CE 2nd, Deierhoi MH, Young C, Curtis JJ, Iskandrian AE
Jazyk: angličtina
Zdroj: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2008 Jun; Vol. 19 (6), pp. 1191-6. Date of Electronic Publication: 2008 Mar 27.
DOI: 10.1681/ASN.2007040503
Abstrakt: Individuals waiting for a renal transplant experience excessive cardiovascular mortality, which is not fully explained by the prevalence of ischemic heart disease in this population. Overt heart failure is known to increase the mortality of patients with ESRD, but the impact of lesser degrees of ventricular systolic dysfunction is unknown. For examination of the association between left ventricular ejection fraction(LVEF) and mortality of renal transplant candidates, the records of 2718 patients evaluated for transplantation at one institution were reviewed. During 6355 patient-years (median 27 mo) of follow-up, 681 deaths occurred. Patients with systolic dysfunction (LVEF
Databáze: MEDLINE