[Genetic load of hereditary diseases in populations of the Krasnodar Krai].

Autor:	Petrin AN, Golubtsov VI, Galkina VA, Ginter EK, Revazov AA, Khisamova MV, Mikhaĭlova LK, Khlevnikova OV, Sukolin GI, Poleshchuk VV
Jazyk:	ruština
Zdroj:	Genetika [Genetika] 1991 Feb; Vol. 27 (2), pp. 345-52.
Abstrakt:	Medico-genetical study of populations living in Krasnodar district was carried out. The mean value of genetic load contributed by autosomal dominant diseases composed 0.92 +/- 0.06, this value being 0.56 +/- 0.04 for autosomal recessive and 0.36 +/- 0.05 for X-linked recessive disorders per one thousand. Comparative analysis of genetical load in urban and rural populations demonstrated that they had no differences in relation to genetical load contributed by autosomal recessive and X-linked recessive disorders. At the same time, significant differences were noted between the populations concerning genetic load contributed by autosomal-dominant disorders.
Databáze:	MEDLINE
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