| Autor: |
Sydow O; Department of Neurology, Karolinska University Hospital, Stockholm, Sweden. |
| Jazyk: |
angličtina |
| Zdroj: |
The FEBS journal [FEBS J] 2008 Apr; Vol. 275 (7), pp. 1370-1376. Date of Electronic Publication: 2008 Feb 12. |
| DOI: |
10.1111/j.1742-4658.2008.06295.x |
| Abstrakt: |
Effective medical treatment for Parkinson's disease has been available for almost 40 years. After several years of treatment with L-dihydroxyphenylalanine (L-dopa, levodopa), however, fluctuations often occur. The patient may then experience random variations of the motor symptoms during the day. The medication becomes increasingly complicated. New therapeutic methods, deep brain stimulation and duodenal infusion of L-dopa, have proven to be very effective in stabilizing the fluctuations. A clinical update of Parkinson's disease is presented together with a short review of these two methods. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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