[Prognostic-factor-related survival in a series of patients with renal cell carcinoma].
| Autor: | Giménez Bachs JM; Servicio de Urología, Complejo Hospitalario Universitario de Albacete, Albacete, España. gbjosem@sescam.jccm.es, Donate Moreno MJ, Salinas Sánchez AS, Pastor Navarro H, Carrión López P, Pastor Guzmán JM, Polo Ruíz L, Martínez Martín M, Ruíz Mondéjar R, Virseda Rodríguez JA |
|---|---|
| Jazyk: | Spanish; Castilian |
| Zdroj: | Archivos espanoles de urologia [Arch Esp Urol] 2007 Dec; Vol. 60 (10), pp. 1.167-1.174. |
| DOI: | 10.4321/s0004-06142007001000004 |
| Abstrakt: | Objectives: To analyze the survival rate in a series of patients with the diagnosis of renal cell carcinoma over a 19 year period based on prognostic factors usually employed in clinical practice. Methods: Retrospective study of 259 consecutive patients with the diagnosis of renal cell carcinoma undergoing surgery in our department between 1988 and 2006. From clinical, pathological, and follow-up data we performed a survival study comparing the impact of usual prognostic factors: stage, tumor size, nuclear grade, etc. Results: 264 surgical procedures were performed in 259 patients, with a mean age of 6 1.91 yr. The most frequent way of diagnosis was incidental finding (52.12% of the cases); radical nephrectomy was performed in 72.97% of the cases in comparison with 26.25% partial nephrectomies. Clear cell carcinoma was the most frequent histological diagnosis (69.88%). Patients with clear cell carcinoma, symptomatic tumors, bigger size, and greater Fuhrman nuclear grade presented worse survivals, mainly in tumors with stage >pT3a. The presence of involved lymph nodes or distant metastases is associated with a much lower cancer-specific survival. Global five-year cancer-specific survival was over 80%. Conclusions: The classical prognostic factors used to predict survival in renal cancer are still useful, mainly pathological stage pT. We observed a better survival in comparison with older series, but this kind of tumors continue generating important morbidity-mortality. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|