[Short duration of initial intravenous treatment in 70 pediatric patients with osteoarticular infections].
| Autor: | Prado S MA; Unidad de Infectología, Servicio de Pediatría, Hospital Dr. Sótero Del Río, Santiago, Chile., Lizama C M, Peña D A, Valenzuela M C, Viviani S T |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia [Rev Chilena Infectol] 2008 Feb; Vol. 25 (1), pp. 30-6. Date of Electronic Publication: 2008 Feb 08. |
| DOI: | /S0716-10182008000100007 |
| Abstrakt: | Unlabelled: Osteoarticular infections (OAI) are infrequent in pediatrics and there is controversy on the need for prolonged use of intravenous antimicrobials. Objective: To characterize and describe evolution and complications of a regimen of 7 days initial intravenous antibiotic treatment for OAI in children, completing 4-6 weeks of total treatment. Patients and Methods: In a large pediatric hospital, 70 children younger than 15 years of age were diagnosed with OAI between March 2003 and December 2004. Children received 7 days of intravenous antibiotics followed by 3 to 5 weeks of oral treatment. Results: Incidence of OAI in this hospital was 1.8:10000. Patients mean age was 6.4 +/-4.4 years and 60% presented with septic arthritis, 36% osteomyelitis and 4% osteoarthritis. In 80% of cases, the infection was located in the lower extremity. Positive cultures were obtained in 59% predominating Staphylococcus aureus (46.5%). Seven patients had prolonged pain or persistently high or increasing serum C reactive protein levels and were maintained on prolonged intravenous therapy. None of the 63 children with 7 day intravenous antimicrobials nor the 7 children with prolonged intravenous use developed a complication in the short-term follow up. Conclusions: Seven days of intravenous antibiotic for the initial phase of OAI treatment was effective in a majority of children and may be recommended. |
| Databáze: | MEDLINE |
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