Separate synthesis and evaluation of glucitol bis-phosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases.

Autor:	Mabiala-Bassiloua CG; ECBB, ICMMO, Univ Paris-Sud, UMR 8182, F-91405 Orsay, France., Zwolinska M, Therisod H, Sygusch J, Therisod M
Jazyk:	angličtina
Zdroj:	Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 Mar 01; Vol. 18 (5), pp. 1735-7. Date of Electronic Publication: 2008 Jan 26.
DOI:	10.1016/j.bmcl.2008.01.076
Abstrakt:	We report the first unambiguous syntheses of glucitol-1,6-bis-phosphate and mannitol-1,6-bis-phosphate and their competitive inhibition of various fructose bis-phosphate aldolases.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu Full Text from ScienceDirect