| Autor: |
van Beers EJ, Nieuwdorp M, Duits AJ, Evers LM, Schnog JJ, Biemond BJ |
| Jazyk: |
angličtina |
| Zdroj: |
Haematologica [Haematologica] 2008 Feb; Vol. 93 (2), pp. 307-8. |
| DOI: |
10.3324/haematol.12027 |
| Abstrakt: |
The glycocalyx is an important anti-inflammatory and anti-adhesive barrier at the luminal side of endothelial cells. Glycocalyx volume was significantly reduced in sickle cell patients (HbSS/HbSbeta(0)-thalassemia median 0.47L, IQR 0.27-0.66, HbSC/HbSbeta(+)-thalassemia 0.23L, 0.0-0.58) compared with controls (1 x 10(9)L, 0.52-1.77) (p=0.03). Reduced glycocalyx may be a new factor in the pathophysiology of sickle cell disease. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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