Insect growth regulatory effects of linear diterpenoids and derivatives from Baccharis thymifolia.

Autor: Juan Hikawczuk VE; Facultad de Química, Bioquíca y Farmacia, Universidad Nacional de San Luis, Chacabuco y Pedernera, 5700 San Luis, Argentina., Saad JR, Giordano OS, García C, Martín T, Martín VS, Sosa ME, Tonn CE
Jazyk: angličtina
Zdroj: Journal of natural products [J Nat Prod] 2008 Feb; Vol. 71 (2), pp. 190-4. Date of Electronic Publication: 2008 Jan 31.
DOI: 10.1021/np070392o
Abstrakt: Linear diterpenes isolated from aerial parts of Baccharis thymifolia ( 1- 3) were tested for insect growth inhibitory activity against Tenebrio molitor larvae. Compounds 4- 16 were prepared by various chemical transformations. The diterpenes 6,10-( E,E)-thymifodioic acid ( 1), the butenolide 3, and the derivatives 4, 11, and 14 produced developmental deficiencies in assays using topical application on fifth instar larvae of T. molitor. Compound 3 is a new natural product.
Databáze: MEDLINE