| Autor: |
Hibi M; Department of Pediatric Surgery, Fujita Health University, Toyoake, Aichi, Japan. mhibi@fujita-hu.ac.jp, Hara F, Tomishige H, Nishida Y, Kato T, Okumura N, Hashimoto T, Kato R |
| Jazyk: |
angličtina |
| Zdroj: |
Pediatric hematology and oncology [Pediatr Hematol Oncol] 2008 Jan-Feb; Vol. 25 (1), pp. 73-8. |
| DOI: |
10.1080/08880010701774033 |
| Abstrakt: |
Humoral hypercalcemia of malignancy (HHM) is a rare complication of malignant pediatric tumors, specifically those that secrete humoral factor(s), such as parathyroid hormone-related peptide (PTHrP). The authors report a case of severe hypercalcemia associated with ovarian dysgerminoma in a 10-year-old girl. In this case, the humoral factor was considered to be 1,25-dihydroxyvitamin D. HHM is extremely resistant to medical therapy. Therefore, tumor resection or volume reduction is necessary to control serum calcium levels. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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