| Autor: |
Rao SG; Cypress Bioscience, Inc., San Diego, CA, USA., Gendreau JF, Kranzler JD |
| Jazyk: |
angličtina |
| Zdroj: |
Psychopharmacology bulletin [Psychopharmacol Bull] 2007; Vol. 40 (4), pp. 24-67. |
| Abstrakt: |
The fibromyalgia syndrome (FMS) is the most frequent cause of chronic, widespread pain. This review, which is targeted at the psychiatry and psychopharmacology communities, summarizes the state-of-the-art as it relates to both the pathophysiology and treatment of FMS. Toward this end, the anatomy and physiology of pain pathways are summarized, followed by a review of the altered biology of pain processing, neurotransmitter function, and neuroendocrine systems in FMS. The categories of current drugs employed to treat the disorder are detailed, along with a critical review of the literature supporting such use. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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