| Autor: |
Ibrahim AS; Division of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California--Los Angeles Medical Center, Torrance, CA 90502, USA. ibrahim@labiomed.org, Gebremariam T, Husseiny MI, Stevens DA, Fu Y, Edwards JE Jr, Spellberg B |
| Jazyk: |
angličtina |
| Zdroj: |
Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2008 Apr; Vol. 52 (4), pp. 1573-6. Date of Electronic Publication: 2008 Jan 28. |
| DOI: |
10.1128/AAC.01488-07 |
| Abstrakt: |
We compared the efficacies of liposomal amphotericin B (LAmB) and an amphotericin B lipid complex (ABLC) in diabetic ketoacidotic (DKA) or neutropenic mice with disseminated zygomycosis. ABLC was as effective as LAmB in neutropenic but not DKA mice. Low-dose ABLC was less effective than LAmB at reducing brain fungal burdens in both models. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
