| Autor: |
Mangusheva NA; Ul'yanovsk State Pedagogic Institute, Russia., Katalymov LL |
| Jazyk: |
angličtina |
| Zdroj: |
Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2007 Mar; Vol. 143 (3), pp. 295-8. |
| DOI: |
10.1007/s10517-007-0093-z |
| Abstrakt: |
The development of tonic and use-dependent block of nerve conduction under the effect of antiarrhythmic drug ajmaline and local anesthetic lidocaine was examined on sciatic nerve of Rana ridibunda. Ajmaline and lidocaine attenuated the amplitude of action potential by half during 120 and 13 minutes, respectively. Ajmaline produced virtually immediate use-dependent block of conductance, while it was minor in lidocaine-treated nerve preparation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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