| Autor: |
Perea EJ; Departamento de Microbiología, Facultad de Medicina de Sevilla., García-López JL, Martín R, Calmet M, Cisterna R, Estébanez V, Vázquez JA, Martín Luengo F, Altuna A, Merino C, et. al. |
| Jazyk: |
Spanish; Castilian |
| Zdroj: |
Enfermedades infecciosas y microbiologia clinica [Enferm Infecc Microbiol Clin] 1991 Dec; Vol. 9 (10), pp. 619-23. |
| Abstrakt: |
To study N. gonorrhoeae resistance in Spain. We evaluate 402 strains consecutively isolated in 7 Spanish cities (Barcelona, Bilbao, Madrid, Murcia, Seville, Valencia and Valladolid). The MIC to 9 antimicrobial agents was determined by agar-dilution (DST) method. We found a high incidence (15.7%) of penicillinase producer strains (NGPP). Most (53.3%) of all non-NGPP strains showed reduced sensitivity to penicillin and 1.5% of the strains had chromosomally mediated resistance. All NGPP strains and 90% of non-NGPP strains showed reduced sensitivity to tetracycline (MIC greater than 0.23 mg/l). We did not found any strain with high-level tetracycline resistance. MIC90 for the other drugs tested were: erythromycin, 0.125 mg/l; spectinomycin, 16 mg/l; cefoxitin, 2 mg/l; cefuroxime 0.06 mg/l; ceftriaxone 0.0037 mg/l; ofloxacin 0.06 mg/l and ciprofloxacin, 0.0018 mg/l. NGPP are very prevalent in Spain. Most of these strains had chromosomally mediated resistance to penicillin and tetracycline. We did not found resistance to other antimicrobial agents. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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